EUSA Pharma: against COVID-19 Company

Entity: EUSA Pharma

Category: Treatment Development

Description: EUSA Pharma is a pharmaceutical company developing and licensing late-stage oncology, pain control, and critical care products. EUSA Pharma has ambitious plans to expand its portfolio through acquisition and in-licensing and is led by an experienced management team with a strong record of building successful specialty pharmaceutical companies. The EUSA Pharma business is supported by significant funding raised from leading life science investor Essex Woodlands. In addition to direct commercial operations across the EU and US, EUSA Pharma also has a wide distribution network of commercial partners in Europe, the Middle East, Asia and Latin America and makes products available in approximately 40 countries across the world through this broad international platform.

Project: SISCO (Siltuximab In Serious COVID-19) Study

Summary: Hemel Hempstead company EUSA Pharma has launched an observational study of IL-6 med Sylvant (siltuximab) to treat patients with severe COVID-19, to explore its effectiveness in reducing time required in intensive care, among other things. EUSA Pharma on April 1 announced initial preliminary results from the Papa Giovanni XXIII Hospital-sponsored SISCO (Siltuximab In Serious COVID-19) Study (NCT04322188). Interim data from the first 21 patients treated with Sylvant and followed for up to seven days showed that seven patients experienced a clinical improvement with a reduced need for oxygen support, while another nine patients saw their condition stabilize, indicated by no clinically relevant changes. C-Reactive Protein levels, a marker of systemic inflammation, declined from baseline through to Day 5 following treatment in all 16 patients who showed sufficient recorded values. The next phase of data will compare outcomes in matched case-control patients not treated with Sylvant, and is expected in coming weeks. Twenty-one patients were enrolled in the study, which evaluated Sylvant in COVID-19 patients who had developed serious respiratory complications.
Technology: Treatment Development
Headquarters: United Kingdom
Founded Date: N/A
Employees Number: N/A
Funding Status: N/A

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