Northwestern University. Cancer Biology and Epigenomics Program ^{R&D Centre}

The Cancer Epigenetics & Nuclear Dynamics (CEND) program focuses on nuclear phenomena associated with cancer, how information normally flows to and from the nucleus, and how information changes under tumorigenic conditions. CEND is organized into four thematic groups of researchers that reflect the program’s scientific aims. To achieve these aims, CEND members employ powerful genetic model systems, including budding yeast, C. elegans, Drosophila, and mice. Mechanistic analyses using cancer cell lines, primary cells, and tissue explants, as well as purified in vitro systems of varying complexity, complement studies in these model systems.