University of Cologne. Skin Cancer Center R&D Centre

The Iden laboratory investigates mechanisms underlying cell and tissue polarization, and how molecular regulators of cell polarity control tissue homeostasis and skin cancer. Using mouse genetics and disease models, the scientists assess the impact of impaired cyto-architecture on oncogenic processes. Next to elucidating basic principles of cancer biology, a major goal is to develop new diagnostic and therapeutic approaches to skin cancers and eventually other types of cancer.